• Development and Validation of a Deep Learning Method to Predict Cerebral Palsy From Spontaneous Movements in Infants at High Risk 

      Groos, Daniel; Adde, Lars; Aubert, Sindre Aarnes; Boswell, Lynn; De Regnier, Raye-Ann; Fjørtoft, Toril Larsson; Gaebler-Spira, Deborah; Haukeland, Andreas; Loennecken, Marianne; Msall, Michael; Moinichen, Unn Inger; Pascal, Aurelie; Peyton, Colleen; Ramampiaro, Heri; Schreiber, Michael D.; Silberg, Inger Elisabeth; Songstad, Nils Thomas; Thomas, Niranjan; van den Broeck, Christine; Øberg, Gunn Kristin; Ihlen, Espen Alexander F.; Støen, Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-11)
      Importance Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity. Objective To develop and assess the external validity of a novel deep learning–based method to predict CP based on videos of infants’ spontaneous movements at 9 to 18 weeks’ corrected ...
    • General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit 

      Ustad, Tordis; Fjørtoft, Toril Larsson; Øberg, Gunn Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-14)
      <p><i>Background</i> The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, detailed steps of assessment have been developed – one for preterm and term age, and one for use between 3 and 5 months. One potential benefit of such a detailed analysis ...
    • Machine Learning of Infant Spontaneous Movements for the Early Prediction of Cerebral Palsy: A Multi-Site Cohort Study 

      Ihlen, Espen Alexander F.; Støen, Ragnhild; Boswell, Lynn; de-Regnier, Raye-Ann; Fjørtoft, Toril Larsson; Gaebler-Spira, Deborah; Labori, Cathrine; Loennecken, Marianne; Msall, Michael; Møinichen, Unn Inger; Peyton, Colleen; Schreiber, Michael; Silberg, Inger Elisabeth; Songstad, Nils Thomas; Vågen, Randi; Øberg, Gunn Kristin; Adde, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-18)
      <i>Background</i>: Early identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim of the present study was to present a novel machine-learning model, the Computer-based Infant Movement Assessment (CIMA) model, for clinically feasible early CP prediction based on infant video recordings.<p><p> <i>Methods</i>: The CIMA model was ...
    • The Predictive Accuracy of the General Movement Assessment for Cerebral Palsy: A Prospective, Observational Study of High-Risk Infants in a Clinical Follow-Up Setting 

      Støen, Ragnhild; Boswell, Lynn; De Regnier, Raye-Ann; Fjørtoft, Toril Larsson; Gaebler-Spira, Deborah; Ihlen, Espen Alexander F.; Labori, Cathrine; Loennecken, Marianne; Msall, Michael E.; Moinichen, Unn Inger; Peyton, Colleen; Russow, Annamarie; Schreiber, Michael D.; Silberg, Inger Elisabeth; Songstad, Nils Thomas; Vågen, Randi Tynes; Øberg, Gunn Kristin; Adde, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-25)
      Background: Early prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during the fidgety movements (FM) period has been recommended as standard of care in high-risk infants. The aim of this study was to determine the accuracy of GMA, alone or in combination with neonatal imaging, in predicting cerebral palsy (CP). Methods: Infants with increased risk of perinatal brain ...
    • Two-year motor outcomes associated with the dose of NICU based physical therapy: The Noppi RCT 

      Øberg, Gunn Kristin; Handegård, Bjørn Helge; Campbell, Suzann K.; Ustad, Tordis; Fjørtoft, Toril Larsson; Kaaresen, Per Ivar; Girolami, Gay L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-25)
      Background - Interventions involving both the parent and the preterm infant have demonstrated lasting effects on cognitive outcomes, but motor effects are less salient. It remains unclear when to commence early intervention and if dosages have impact on motor outcomes.<p> <p>Aims - To examine the effect on motor performance at 24-months corrected age following a parent-administered intervention ...